GPCR Cell Lines
From GPCR cell lines to luciferase-labeled tumor cells for in vivo imaging studies, to engineered cells we offer a wide range of cell lines designed to fit your research and development needs.
GPCR cell lines: Over 300 stable GPCR cells lines for binding and functional testing and over 130 cells lines for calcium testing
- AequoScreen® cell lines are doubly transfected to co-express both Aequorin and a variety of GPCRs for calcium flux assays
- ValiScreen® cell lines express a variety of different GPCRs
- PhotoScreen® cell lines include photoprotein kinetic luminescence technology for measuring calcium flux in cells
Luciferase-labeled tumor cell lines: IVISbrite™ bioluminescent tumor cells, for in vivo imaging, are labeled with red-shifted luciferase that offer a brighter signal
Engineered cell lines: With over 7,500 ‘ready-to-go’ cell lines to custom services, Horizon Discovery has the expertise to provide unrivaled cell line engineering solutions
Tag-lite® binding assays
Revvity's Tag-lite binding assays offer straightforward add-and-read protocols to help you characterize the binding properties of compounds, regardless of their chemical structures (peptides, small or complex molecules), or pharmacological properties (agonist, antagonist, or inverse agonist).
Revvity's Tag-lite binding assays offer straightforward add-and-read protocols to help you characterize the binding properties of compounds, regardless of their chemical structures (peptides, small or complex molecules), or pharmacological properties (agonist, antagonist, or inverse agonist).
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Stable, recombinant ValiScreen® cell line expressing α2B Adrenergic receptor, human recombinant in CHO-K1 host cells.
Stable, recombinant ValiScreen® cell line expressing the Chemokine receptor CCR1, human recombinant in CHO-K1 host cells.
Stable, recombinant AequoScreen® cell line expressing aequorin and the Histamine H2 receptor, human recombinant in CHO-K1 host cells.
Stable, recombinant ValiScreen® cell line expressing the Melanocortin MC4 receptor, human recombinant in CHO-K1 host cells.
Stable, recombinant AequoScreen® cell line expressing aequorin and the Melanin-concentrating hormone receptor 2 (MCH2), human recombinant in CHO-K1 host cells.
Stable, recombinant ValiScreen® cell line expressing the N-ormyl peptide receptor 2 (FPR2, FPRL1), human recombinant in CHO-K1 host cells.
Stable, recombinant AequoScreen® cell line expressing aequorin and the Calcitonin receptor AM2, human recombinant in CHO-K1 host cells.
Stable, recombinant AequoScreen® cell line expressing aequorin and the α1B Adrenergic receptor, human recombinant in CHO-K1 host cells.
Stable, recombinant AequoScreen® cell line expressing aequorin and the Chemokine receptor CCR9A, human recombinant in CHO-K1 host cells.
Stable, recombinant ValiScreen® cell line expressing the Prostanoid EP4 receptor, human recombinant in HEK293 host cells.
Stable, recombinant AequoScreen® cell line expressing aequorin and the Neuromedin U receptor NMU1, human recombinant in CHO-K1 host cells.
Stable, recombinant PhotoScreen® cell line expressing a photoprotein and the Adenosine A3 receptor, human recombinant in CHO-K2 host cells.
Stable, recombinant AequoScreen® cell line expressing aequorin and the Serotonin receptor 5-HT2B, human recombinant in CHO-K1 host cells.
Stable, recombinant ValiScreen® cell line expressing the Histamine H2 receptor, human recombinant in CHO-K1 host cells.
Stable, recombinant AequoScreen® cell line expressing aequorin and the Chemokine receptor CXCR6, human recombinant in CHO-K1 host cells.
Stable, recombinant AequoScreen® cell line expressing aequorin and the Motilin receptor, human recombinant in CHO-K1 host cells.
Stable, recombinant ValiScreen® cell line expressing the Opioid delta receptor, human recombinant in CHO-K1 host cells.
Stable, recombinant AequoScreen® cell line expressing aequorin and the QRFP (GPR103) receptor, human recombinant in CHO-K1 host cells. This receptor was formally known as the Peptide P518 receptor and OX2-like receptor.
Stable, recombinant AequoScreen® cell line expressing aequorin and the Galanin receptor GAL2, human recombinant in CHO-K1 host cells.
Stable, recombinant ValiScreen® cell line expressing the Orexin receptor type 1 (OR1, human recombinant in CHO-K1 host cells.
Stable, recombinant ValiScreen® cell line expressing the Chemokine receptor CCR3, human recombinant in K562 host cells.
Stable, recombinant ValiScreen® cell line expressing the Muscarinic acetylcholine M2 receptor, human recombinant in CHO-K1 host cells.
Stable, recombinant ValiScreen® cell line expressing the Cholecystokinin receptor CCK2, human recombinant in 1321N1 host cells.
Stable, recombinant PhotoScreen® cell line expressing a photoprotein and the rotensin receptor UT (Uro II, GPR14), human recombinant in CHO-K1 host cells.
Stable, recombinant AequoScreen® parental cell line expressing aequorin and Gα16 in HEK293 host cells.